The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2009

Filed:

Aug. 26, 2004
Applicants:

Takaharu Tsutsumi, Hino, JP;

Satoshi Sugiura, Hino, JP;

Masahiro Koga, Hino, JP;

Yoshiyuki Matsumoto, Hino, JP;

Toshihiro Ishii, Hino, JP;

Akira Nakano, Hino, JP;

Gen Unoki, Hino, JP;

Yuri Sakai, Hino, JP;

Reiko Takarada, Hino, JP;

Hiroko Ogawa, Hino, JP;

Inventors:

Takaharu Tsutsumi, Hino, JP;

Satoshi Sugiura, Hino, JP;

Masahiro Koga, Hino, JP;

Yoshiyuki Matsumoto, Hino, JP;

Toshihiro Ishii, Hino, JP;

Akira Nakano, Hino, JP;

Gen Unoki, Hino, JP;

Yuri Sakai, Hino, JP;

Reiko Takarada, Hino, JP;

Hiroko Ogawa, Hino, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/04 (2006.01); A61P 25/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound having GSK-3 inhibitory activity. Aand Aare a single bond, an aliphatic hydrocarbon group; Aand Aare a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; Gis a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; Gis H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; Ais a single bond, NR; Ris H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; Ais a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; Ris H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and Rmay be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when Ais CR═CR or C≡C, wherein R is H or an lower aliphatic hydrocarbon group.


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