The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2009

Filed:

Oct. 05, 2005
Applicants:

Yasuhiro Yonetoku, Tokyo, JP;

Kenji Negoro, Tokyo, JP;

Kenichi Onda, Tokyo, JP;

Masahiko Hayakawa, Tokyo, JP;

Daisuke Sasuga, Tokyo, JP;

Takahiro Nigawara, Tokyo, JP;

Kazuhiko Iikubo, Tokyo, JP;

Hiroyuki Moritomo, Tokyo, JP;

Shigeru Yoshida, Tokyo, JP;

Takahide Ohishi, Tokyo, JP;

Inventors:

Yasuhiro Yonetoku, Tokyo, JP;

Kenji Negoro, Tokyo, JP;

Kenichi Onda, Tokyo, JP;

Masahiko Hayakawa, Tokyo, JP;

Daisuke Sasuga, Tokyo, JP;

Takahiro Nigawara, Tokyo, JP;

Kazuhiko Iikubo, Tokyo, JP;

Hiroyuki Moritomo, Tokyo, JP;

Shigeru Yoshida, Tokyo, JP;

Takahide Ohishi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 3/10 (2006.01); C07D 495/04 (2006.01); C07D 279/12 (2006.01); C07D 417/04 (2006.01); C07D 413/04 (2006.01); A61K 31/541 (2006.01); A61K 31/5355 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided novel pyrimidine derivatives which has been fused with an aromatic heterocycle selected from thiophene, thiazole and pyridine or pharmaceutically acceptable salts thereof; and a pharmaceutical composition comprising said compound as an active ingredient. These compounds exhibit excellent promoting activity on insulin secretion and activity against hyperglycemia. Hence, the pharmaceutical compositions comprising such compounds as active ingredients, based on these actions, are useful for treating and/or preventing insulin-dependent diabetes (type 1 diabetes), non-insulin-dependent diabetes (type 2 diabetes), insulin-resistant diseases, obesity, and the like.


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