The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Sep. 25, 1997
David C. Rueger, Hopkinton, MA (US);
Thangavel Kuberasampath, Medway, MA (US);
Hermann Oppermann, Medway, MA (US);
Engin Ozkaynak, Milford, MA (US);
Roy H. L. Pang, Etna, NH (US);
Charles M. Cohen, Medway, MA (US);
David C. Rueger, Hopkinton, MA (US);
Thangavel Kuberasampath, Medway, MA (US);
Hermann Oppermann, Medway, MA (US);
Engin Ozkaynak, Milford, MA (US);
Roy H. L. Pang, Etna, NH (US);
Charles M. Cohen, Medway, MA (US);
Stryker Corporation, Kalamazoo, MI (US);
Abstract
Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.