The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Dec. 05, 2007
Andre R. Abad, W. Des Moines, IA (US);
Ronald D. Flannagan, Grimes, IA (US);
Rafael Herrmann, Wilmington, DE (US);
Albert L. LU, Newark, DE (US);
Billy F. Mccutchen, College Station, TX (US);
James K. Presnail, Avondale, PA (US);
Janet A. Rice, Wilmington, DE (US);
James F. Wong, Johnston, IA (US);
Cao-guo Yu, Urbandale, IA (US);
Andre R. Abad, W. Des Moines, IA (US);
Ronald D. Flannagan, Grimes, IA (US);
Rafael Herrmann, Wilmington, DE (US);
Albert L. Lu, Newark, DE (US);
Billy F. McCutchen, College Station, TX (US);
James K. Presnail, Avondale, PA (US);
Janet A. Rice, Wilmington, DE (US);
James F. Wong, Johnston, IA (US);
Cao-Guo Yu, Urbandale, IA (US);
Pioneer Hi-Bred International, Inc., Johnston, IA (US);
E.I. du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds.