The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2009
Filed:
Aug. 21, 2003
Gary Brian Evans, Lower Hutt, NZ;
Richard Hubert Furneaux, Wilton, NZ;
Dirk Henning Lenz, Wellington, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Northland, NZ;
Olga Vladimirovna Zubkova, Wellington, NZ;
Gary Brian Evans, Lower Hutt, NZ;
Richard Hubert Furneaux, Wilton, NZ;
Dirk Henning Lenz, Wellington, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Northland, NZ;
Olga Vladimirovna Zubkova, Wellington, NZ;
Industrial Research Limited, Auckland, NZ;
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Abstract
The present invention relates to compounds of the general formula (I) which are inhibitors of purine muclioside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5'-methylthioadenosine phosphorylases (MTAP), 5′-methylthioadenosine mucliosidases (MTAN) and/or nucleoside hydrolases (NH). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.