The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2009

Filed:

Apr. 19, 2007
Applicants:

Alexander Michael Porte, Pennington, NJ (US);

Thomas Joseph Caggiano, Morrisville, PA (US);

George Diamantidis, Randolph, NJ (US);

Diane Barbara Hauze, Radnor, PA (US);

Boyd Lynn Harrison, Princeton Junction, NJ (US);

Molly Hoke, Hightstown, NJ (US);

Anthony Kreft, Langhorne, PA (US);

Dennis M. Kubrak, Philadelphia, PA (US);

Charles William Mann, Philadelphia, PA (US);

Scott Mayer, Bridgewater, NJ (US);

Koi Michele Morris, Plainsboro, NJ (US);

Inventors:

Alexander Michael Porte, Pennington, NJ (US);

Thomas Joseph Caggiano, Morrisville, PA (US);

George Diamantidis, Randolph, NJ (US);

Diane Barbara Hauze, Radnor, PA (US);

Boyd Lynn Harrison, Princeton Junction, NJ (US);

Molly Hoke, Hightstown, NJ (US);

Anthony Kreft, Langhorne, PA (US);

Dennis M. Kubrak, Philadelphia, PA (US);

Charles William Mann, Philadelphia, PA (US);

Scott Mayer, Bridgewater, NJ (US);

Koi Michele Morris, Plainsboro, NJ (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 311/01 (2006.01); C07C 307/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of Formula (I), or pharmaceutically acceptable salts and/or hydrates or prodrugs thereof, wherein Formula (I) has the structure: is provided, wherein R-Rare defined herein. These compounds are useful in medicaments for treating a disease selected from the group consisting of Alzheimer's Disease, amyloid angiopathy, cerebral amyloid angiopathy, systemic amyloidosis, hereditary cerebral hemorrhage with amyloidosis of the Dutch type, inclusion body myositis, mild cognitive impairment (MCI) and Down's syndrome, in a subject.


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