The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2009
Filed:
May. 02, 2007
Applicants:
Liu Xing, Shanghai, CN;
He Xungui, Shanghai, CN;
Yuan Wang, Shanghai, CN;
Michel Bekhazi, Pointe Claire, CA;
Sonia Krivonos, Beer Sheva, IL;
Edna Danon, Meitar, IL;
Inventors:
Liu Xing, Shanghai, CN;
He Xungui, Shanghai, CN;
Yuan Wang, Shanghai, CN;
Michel Bekhazi, Pointe Claire, CA;
Sonia Krivonos, Beer Sheva, IL;
Edna Danon, Meitar, IL;
Assignee:
Chemagis Ltd., Bnei Brak, IL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided is a process for producing imatinib and salts thereof, e.g., imatinib mesylate. The process includes reacting 4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid with N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine in the presence of a carboxylic acid coupling reagent, to produce imatinib, and optionally converting the imatinib into a salt.