The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2009
Filed:
Jun. 23, 2006
Yoshihiko Kotake, Ibaraki, JP;
Jun Niijima, Ibaraki, JP;
Yoshio Fukuda, Ibaraki, JP;
Mitsuo Nagai, Ibaraki, JP;
Regina Mikie Kanada, Ibaraki, JP;
Takashi Nakashima, Shizuoka, JP;
Masahi Yoshida, Shizuoka, JP;
Toshio Tsuchida, Shizuoka, JP;
Yoshihiko Kotake, Ibaraki, JP;
Jun Niijima, Ibaraki, JP;
Yoshio Fukuda, Ibaraki, JP;
Mitsuo Nagai, Ibaraki, JP;
Regina Mikie Kanada, Ibaraki, JP;
Takashi Nakashima, Shizuoka, JP;
Masahi Yoshida, Shizuoka, JP;
Toshio Tsuchida, Shizuoka, JP;
Eisai R& D Management Co., Ltd., Tokyo, JP;
Merican Corporation, Tokyo, JP;
Abstract
The present invention relates to a compound represented by the formula (I): (wherein, R, R, Rand Rare the same as or different from one another and each represents a hydroxyl group etc.), a pharmacologically acceptable salt thereof or a hydrate of them. The compound (I) of the present invention suppresses angiogenesis, in particular, suppresses VEGF production in a hypoxic condition and is useful as a therapeutic agent for treating solid cancer.