The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2009

Filed:

Aug. 24, 2005
Applicants:

Valerjans Kauss, Riga, LV;

Ieva Jaunzeme, Riga, LV;

Aigars Jirgensons, Riga, LV;

Ivars Kalvinsh, Salaspils, LV;

Maksims Vanejevs, Riga, LV;

Markus Henrich, Wetzlar, DE;

Wojciech Danysz, Nidderau, DE;

Claudia Jatzke, Frankfurt am Main, DE;

Christopher Graham Raphael Parsons, Nidderau, DE;

Tanja Weil, Heidelberg, DE;

Inventors:

Valerjans Kauss, Riga, LV;

Ieva Jaunzeme, Riga, LV;

Aigars Jirgensons, Riga, LV;

Ivars Kalvinsh, Salaspils, LV;

Maksims Vanejevs, Riga, LV;

Markus Henrich, Wetzlar, DE;

Wojciech Danysz, Nidderau, DE;

Claudia Jatzke, Frankfurt am Main, DE;

Christopher Graham Raphael Parsons, Nidderau, DE;

Tanja Weil, Heidelberg, DE;

Assignee:

Merz Pharma GmbH & Co. KGAA, Frankfurt Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to ethynyl-substituted tetrahydroquinolinone derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group I mGluR modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders.


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