The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2009
Filed:
Aug. 02, 2004
Pierre Deslongchamps, Québec, CA;
Yves Dory, Québec, CA;
Luc Ouellet, Québec, CA;
Gérald Villeneuve, Québec, CA;
Mahesh Ramaseshan, Sunnyvale, CA (US);
Daniel Fortin, Québec, CA;
Mark L. Peterson, Québec, CA;
Hamid R. Hoveyda, Brussels, BE;
Sylvie Beaubien, Québec, CA;
Éric Marsault, Québec, CA;
Graeme L. Fraser, Rixensart, BE;
Pierre Deslongchamps, Québec, CA;
Yves Dory, Québec, CA;
Luc Ouellet, Québec, CA;
Gérald Villeneuve, Québec, CA;
Mahesh Ramaseshan, Sunnyvale, CA (US);
Daniel Fortin, Québec, CA;
Mark L. Peterson, Québec, CA;
Hamid R. Hoveyda, Brussels, BE;
Sylvie Beaubien, Québec, CA;
Éric Marsault, Québec, CA;
Graeme L. Fraser, Rixensart, BE;
Tranzyme Pharma Inc., Quebec, CA;
Abstract
Novel spatially-defined macrocyclic compounds incorporating peptide bond surrogates are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor.