The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2009

Filed:

Nov. 29, 2007
Applicants:

Conor F. Lundergan, Ellicott City, MD (US);

Harry B. Burke, Glen Allen, VA (US);

Timothy A. Mccaffrey, Silver Spring, MD (US);

Inventors:

Conor F. Lundergan, Ellicott City, MD (US);

Harry B. Burke, Glen Allen, VA (US);

Timothy A. McCaffrey, Silver Spring, MD (US);

Assignee:

CapGen Sciences, Inc., Elliocott City, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); C12Q 1/68 (2006.01); C12M 1/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for predicting whether or not a patient is likely to experience restenosis after the placement of a bare metal stent are provided. The methods involve detecting and analyzing gene expression patterns of the cellular components of whole blood, where activation of selected genes has been found to be indicative of a high probability of restenosis. The method thus allows the identification, prior to placement of a stent, of patients who are i) likely to experience restenosis, and thus should receive a stent that includes anti-restenosis agents; or ii) unlikely to experience restenosis, and thus should receive a stent without anti-stenosis agents.


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