The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2009

Filed:

Jan. 18, 2005
Applicants:

Merouane Bencherif, Winston-Salem, NC (US);

Ronald J. Lukas, Phoenix, AZ (US);

Inventors:

Merouane Bencherif, Winston-Salem, NC (US);

Ronald J. Lukas, Phoenix, AZ (US);

Assignees:

Targacept, Inc., Winston-Salem, NC (US);

Catholic Healthcare West, San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01); C12N 1/21 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A chimeric nAChR receptor subunit polypeptide having a substitution of at least about 15% of the native amino acid sequence of the subunit in the area of the C-terminal cytoplasmic domain is provided, as well as polynucleotides encoding the polypeptide. Vectors, host cells, and related methods for evaluating compounds are also provided.


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