The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2009
Filed:
Jun. 17, 2004
Maurice M. Moloney, Calgary, CA;
Joseph Boothe, Calgary, CA;
Richard Keon, Calgary, CA;
Cory Nykiforuk, Calgary, CA;
Gijs Van Rooijen, Calgary, CA;
Maurice M. Moloney, Calgary, CA;
Joseph Boothe, Calgary, CA;
Richard Keon, Calgary, CA;
Cory Nykiforuk, Calgary, CA;
Gijs Van Rooijen, Calgary, CA;
SemBioSys Genetics Inc., Calgary, Alberta, CA;
Abstract
Commercial production of human insulin can be affected via transgenic expression in plant seeds. Thus, levels of insulin accumulation exceeding 0.1% of total cellular protein can be achieved recombinantly, through expression of the insulin with a single-chain antibody as a fusion partner. Production in seeds offers flexibility in storage and shipment of insulin as a raw material, and insulin retains its activity upon extraction from stored seed. Further, the amount of biomass subjected to extraction is limited, due to the relatively low water content of plant seeds.