The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2009

Filed:

Dec. 19, 2006
Applicants:

James B. Doherty, Montvale, NJ (US);

Meng-hsin Chen, Westfield, NJ (US);

Luping Liu, Plainsboro, NJ (US);

Swaminathan R. Natarajan, Scotch Plains, NJ (US);

Robert M. Tynebor, Woodbridge, NJ (US);

Inventors:

James B. Doherty, Montvale, NJ (US);

Meng-Hsin Chen, Westfield, NJ (US);

Luping Liu, Plainsboro, NJ (US);

Swaminathan R. Natarajan, Scotch Plains, NJ (US);

Robert M. Tynebor, Woodbridge, NJ (US);

Assignee:

Merck & Co. Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to potent potassium channel blocker compounds of Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.


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