The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2009
Filed:
Jul. 19, 2005
Mara Boenitz-dulat, Tutzing, DE;
Jessica Laggerbauer, München, DE;
Rainer Schmuck, Benediktbeuern, DE;
Peter Kratzsch, Penzberg, DE;
Wolfgang-reinhold Knappe, Ludwigshafen, DE;
Mara Boenitz-Dulat, Tutzing, DE;
Jessica Laggerbauer, München, DE;
Rainer Schmuck, Benediktbeuern, DE;
Peter Kratzsch, Penzberg, DE;
Wolfgang-Reinhold Knappe, Ludwigshafen, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH) comprising an amino acid insertion between positions 428 and 429 as corresponding to the amino acid sequence known from, to genes encoding such variant s-GDH, to proteins of such s-GDH variants with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugars, especially of glucose in a sample.