The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2009
Filed:
Jan. 05, 2007
Jiang X. Behan, Edison, NJ (US);
Joseph A. Hedrick, South River, NJ (US);
Thomas M. Laz, Parlin, NJ (US);
Frederick James Monsma, Jr., Summit, NJ (US);
Kelley L. Morse, Livingston, NJ (US);
Shelby P. Umland, Boonton Township, NJ (US);
Suke Wang, Edison, NJ (US);
Jiang X. Behan, Edison, NJ (US);
Joseph A. Hedrick, South River, NJ (US);
Thomas M. Laz, Parlin, NJ (US);
Frederick James Monsma, Jr., Summit, NJ (US);
Kelley L. Morse, Livingston, NJ (US);
Shelby P. Umland, Boonton Township, NJ (US);
Suke Wang, Edison, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.