The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2009
Filed:
Apr. 15, 2004
Bernardus Petrus Hubertus Peeters, Lelystad, NL;
Olav Sven DE Leeuw, Almere, NL;
Guus Koch, Lelystad, NL;
Arnoud Leonard Josef Gielkens, Lelystad, NL;
Bernardus Petrus Hubertus Peeters, Lelystad, NL;
Olav Sven de Leeuw, Almere, NL;
Guus Koch, Lelystad, NL;
Arnoud Leonard Josef Gielkens, Lelystad, NL;
Abstract
The invention relates to the process for generating infectious Newcastle disease virus (NDV) entirely from cloned full-length cDNA and to the use of vaccines and diagnostic assays generated with and derived from said process. The process offers the possibility to modify the NDV genome by means of genetic modification and allows the introduction of mutations, deletions and/or insertions. The process can be used to modify the virulence of NDV, thereby generating new attenuated live vaccines with enhanced properties. The process can be used to modify the antigenic make-up of NDV, thus allowing the generation of live NDV marker vaccines which can be serologically distinguished from NDV field strains.