The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2009
Filed:
Dec. 20, 2006
Applicants:
David Thomas, Houston, TX (US);
Mark DE Boer, Cm Utrecht, NL;
Pieter C. J. M. Res, Haarlem, NL;
Peter J. Simone, Hillegom, NL;
Inventors:
David Thomas, Houston, TX (US);
Mark De Boer, Cm Utrecht, NL;
Pieter C. J. M. Res, Haarlem, NL;
Peter J. Simone, Hillegom, NL;
Assignee:
Pangenetics BV, Utrecht, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C12N 5/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells ('APCs'), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection.