The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2009

Filed:

Mar. 25, 2005
Applicants:

Roy Hom, San Francisco, CA (US);

John Tucker, San Diego, CA (US);

Varghese John, San Francisco, CA (US);

Neerav Shah, San Mateo, CA (US);

Inventors:

Roy Hom, San Francisco, CA (US);

John Tucker, San Diego, CA (US);

Varghese John, San Francisco, CA (US);

Neerav Shah, San Mateo, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); A61K 31/18 (2006.01); C07C 233/36 (2006.01); C07C 311/05 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of the formula: where variables Q, Z, X, R, R, R, and Rare defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.


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