The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2009

Filed:

Dec. 16, 2004
Applicants:

Scott Eugene Connor, Indianapolis, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Guoxin Zhu, Noblesville, IN (US);

Robert Jason Herr, Voorheesville, NY (US);

Inventors:

Scott Eugene Connor, Indianapolis, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Guoxin Zhu, Noblesville, IN (US);

Robert Jason Herr, Voorheesville, NY (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds represented by the following structural formula, Formula (I), and stereoisomers, pharmaceutically acceptable salts, solvates and hydrates thereof, wherein: (a) R2 is selected from the group consisting of C-Calkyl and C-heteroalkyl; (b) X is selected from the group consisting of a single bond, O, S, S(O)and N; (c) U is an aliphatic linker wherein one carbon atom of the aliphatic linker is optionally replaced with O, NH or S, and wherein such aliphatic linker is optionally substituted with from one to four substituents each independently selected from R30; (d) Y is selected from the group consisting of C, O, S, NH and a single bond; and (e) E is C(R3)(R4)A or A.


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