The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2009

Filed:

Aug. 19, 2005
Applicants:

Mark T. Bilodeau, Lansdale, PA (US);

Nicholas D. P. Cosford, San Diego, CA (US);

John C. Hartnett, Philadelphia, PA (US);

Yiwei LI, San Diego, CA (US);

Jun Liang, Palo Alto, CA (US);

Peter J. Manley, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

Tony Siu, Brookline, MA (US);

Zhicai Wu, Quakertown, PA (US);

Inventors:

Mark T. Bilodeau, Lansdale, PA (US);

Nicholas D. P. Cosford, San Diego, CA (US);

John C. Hartnett, Philadelphia, PA (US);

Yiwei Li, San Diego, CA (US);

Jun Liang, Palo Alto, CA (US);

Peter J. Manley, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

Tony Siu, Brookline, MA (US);

Zhicai Wu, Quakertown, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/541 (2006.01); A61K 31/5355 (2006.01); A61K 31/519 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds which contain substituted 5-deazapteridine moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.


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