The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2009
Filed:
Feb. 14, 2005
David M. Goldenberg, Mendham, NJ (US);
Hans J. Hansen, Picayune, MS (US);
Chien-hsing Ken Chang, Downingtown, PA (US);
Sailaja S. Vanama, Monroe, NJ (US);
Edmund A. Rossi, Nutley, NJ (US);
David M. Goldenberg, Mendham, NJ (US);
Hans J. Hansen, Picayune, MS (US);
Chien-Hsing Ken Chang, Downingtown, PA (US);
Sailaja S. Vanama, Monroe, NJ (US);
Edmund A. Rossi, Nutley, NJ (US);
Immunomedics, Inc., Morris Plains, NJ (US);
Abstract
Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may be used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile