The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2009
Filed:
Jan. 27, 2009
Ronan O'hagan, Arlington, MA (US);
H. Heidi Okamura, Brookline, MA (US);
Alisa C. Bell, Burlington, MA (US);
Jeanine Lorusso, Ashland, MA (US);
Ronan O'Hagan, Arlington, MA (US);
H. Heidi Okamura, Brookline, MA (US);
Alisa C. Bell, Burlington, MA (US);
Jeanine Lorusso, Ashland, MA (US);
AVEO Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The disclosure provides a method for identifying cancer tissue sensitive to treatment with an inhibitor of Notch receptor activation. The method comprises determining the level of HeyL gene expression in a sample derived from the cancer tissue, wherein an elevated level of HeyL gene expression alone in the sample indicates sensitivity to the cancer tissue to treatment with an inhibitor of Notch receptor activation.