The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2009
Filed:
Mar. 05, 2007
Stefanie Keil, Hofheim, DE;
Maike Glien, Wiesbaden, DE;
Hans-ludwig Schaefer, Hochheim, DE;
Wolfgang Wendler, Selters, DE;
Patrick Bernardelli, Villepreux, FR;
Corinne Terrier, Livry Gargan, FR;
Baptiste Ronan, Clamart, FR;
Stefanie Keil, Hofheim, DE;
Maike Glien, Wiesbaden, DE;
Hans-Ludwig Schaefer, Hochheim, DE;
Wolfgang Wendler, Selters, DE;
Patrick Bernardelli, Villepreux, FR;
Corinne Terrier, Livry Gargan, FR;
Baptiste Ronan, Clamart, FR;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates generally to compounds and compositions for the treatment of metabolic diseases and specifically, the present invention relates to compounds that therapeutically modulation and control lipid and/or carbohydrate metabolism and are thus suitable for the prevention and/or treatment of diseases such as type 2 diabetes, atherosclerosis, and the diverse manifestations thereof. The present invention relates to 7-azaindoles, their physiologically acceptable salts and functional derivatives thereof that exhibit a high degree of peroxisome proliferator-activated receptors (PPAR) agonist activity. Compounds of the present invention are described by formula I: in which the R-groups are herein defined, together with their pharmaceutically acceptable salts, therapeutic methods for their use and processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved.