The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2009

Filed:

Dec. 15, 2006
Applicants:

Bernd Buettelmann, Schopfheim, DE;

BO Han, Shanghai, CN;

Henner Knust, Rheinfelden, DE;

Andreas Koblet, Bottmingen, CH;

Andrew Thomas, Binningen, CH;

Inventors:

Bernd Buettelmann, Schopfheim, DE;

Bo Han, Shanghai, CN;

Henner Knust, Rheinfelden, DE;

Andreas Koblet, Bottmingen, CH;

Andrew Thomas, Binningen, CH;

Assignee:

Hoffman-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2006.01); A61K 31/4245 (2006.01); C07D 261/06 (2006.01); C07D 271/07 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with isoxazol-4-yl-oxadiazole derivatives of formula wherein This class of compounds has high affinity and selectivity for GABA A α5 receptor binding sites and might be useful as cognitive enhancer or for the treatment of cognitive disorders like Alzheimer's disease.


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