The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2009

Filed:

Nov. 01, 2005
Applicants:

David Roger Borcherding, Bangor, PA (US);

Alexandre Gross, Jersey City, NJ (US);

Patrick W. Shum, Flemington, NJ (US);

Nicole Willard, Doylestown, PA (US);

Brian S. Freed, Phillipsburg, NJ (US);

Inventors:

David Roger Borcherding, Bangor, PA (US);

Alexandre Gross, Jersey City, NJ (US);

Patrick W. Shum, Flemington, NJ (US);

Nicole Willard, Doylestown, PA (US);

Brian S. Freed, Phillipsburg, NJ (US);

Assignee:

Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); A01N 43/42 (2006.01); A01N 43/40 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of Formula (I) and ester prodrugs, pharmaceutically acceptable salts or solvates of such compounds; or ester prodrugs of such salts or solvates; pharmaceutical compositions comprising such compounds, their preparation, and their pharmaceutical use in the treatment of disease states capable of being modulated by the inhibition of p38 kinase and/or tumor necrosis factor (TNF).


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