The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2009
Filed:
Aug. 27, 2004
Subramaniam Ananthan, Birmingham, AL (US);
Richard B. Rothman, Baltimore, MD (US);
Edward J. Bilsky, Biddeford, ME (US);
Frank Porreca, Tucson, AZ (US);
Subramaniam Ananthan, Birmingham, AL (US);
Richard B. Rothman, Baltimore, MD (US);
Edward J. Bilsky, Biddeford, ME (US);
Frank Porreca, Tucson, AZ (US);
Southern Research Institute, Birmingham, AL (US);
Abstract
Compounds represented by the formula: wherein R is Calkyl; Ccycloalkylalkyl; or Calkenyl; R' is H or Calkyl; X is H or OH; Y is alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl or aroyl; and Z is CH or N; provided that X is H, when Z is CH and R is Ccycloalkylalkyl or Calkenyl; prodrugs thereof; and pharmaceutically acceptable salts thereof are provided. Compounds of the above formula are useful as analgesics for treating pain; as immunomodulators, to modulate the behavioral effects of drugs of abuse and to modulate the development of tolerance and dependence to μ agonists.