The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2009

Filed:

May. 07, 2004
Applicants:

Kazutoshi Kuroda, Ichikawa, JP;

Noboru Aoki, Numazu, JP;

Toshiro Ochiai, Sunto-gun, JP;

Akihiro Uchida, Sunto-gun, JP;

Yasuhiro Ishikawa, Sunto-gun, JP;

Makoto Kigoshi, Sunto-gun, JP;

Eiji Hayakawa, Sunto-gun, JP;

Kazuki Asanome, Sunto-gun, JP;

Inventors:

Kazutoshi Kuroda, Ichikawa, JP;

Noboru Aoki, Numazu, JP;

Toshiro Ochiai, Sunto-gun, JP;

Akihiro Uchida, Sunto-gun, JP;

Yasuhiro Ishikawa, Sunto-gun, JP;

Makoto Kigoshi, Sunto-gun, JP;

Eiji Hayakawa, Sunto-gun, JP;

Kazuki Asanome, Sunto-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/06 (2006.01); A61K 31/522 (2006.01);
U.S. Cl.
CPC ...
Abstract

Microcrystals of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione having an average particle size of less than 50 μm; microcrystals of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione having an average particle size of less than 50 μm and a crystallinity of 20% or more or the like, which possess excellent solubility, stability, bioavailability, dispersing property in a pharmaceutical formulation; and the like are provided. A solid pharmaceutical formulation which is characterized by comprising the same is also provided.


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