The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2009
Filed:
Dec. 22, 2005
Growth and differentiation of adult muscle stem cells with activators or inhibitors of wnt signaling
Michael Rudnicki, Gloucester, CA;
Patrick Seale, Brookline, MA (US);
Anna Polesskaya, Villejuif, FR;
Anouk Fortin, Gloucester, CA;
Michael Rudnicki, Gloucester, CA;
Patrick Seale, Brookline, MA (US);
Anna Polesskaya, Villejuif, FR;
Anouk Fortin, Gloucester, CA;
Ottawa Health Research Institute, Ottawa, Ontario, CA;
Abstract
Compositions and methods for modulating proliferation and/or lineage commitment of stem cells by modulating the Wnt signalling pathways. Modulators of the Wnt signalling pathways and screening methods to identify modulators are also provided. The methods of the invention may be conducted in vitro or in vivo to induce or inhibit stem cell proliferation and/or lineage commitment, and are particularly useful for in vivo stimulation of proliferation and/or lineage commitment of resident stem cells in a tissue.