The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2009
Filed:
May. 28, 2003
Vincent Dive, Palaiseau, FR;
André Menez, Magny les Hameaux, FR;
Reto Stocklin, Bernex, CH;
Bertrand Tavitian, Saint Cyr l'Ecole, FR;
Fabrice Beau, Massy, FR;
Bertrand Czarny, Malakoff, FR;
Joël Cotton, Orsay, FR;
Vincent Dive, Palaiseau, FR;
André Menez, Magny les Hameaux, FR;
Reto Stocklin, Bernex, CH;
Bertrand Tavitian, Saint Cyr l'Ecole, FR;
Fabrice Beau, Massy, FR;
Bertrand Czarny, Malakoff, FR;
Joël Cotton, Orsay, FR;
Commissariat a l'Energie Atomique, Paris, FR;
Abstract
The invention relates to an amplification-free method of screening groups of radioactive molecules, comprising at least the following steps: (1) the group of molecules is administered to at least one animal; (2) at least one of the animals is slaughtered and the tissue distribution of the radioactivity of the molecules administered is analyzed in vivo; (3) sections of tissue or organs in which a radioactivity signal is detected are selected; (4) radioactive fractions from the sections of tissue or organs are isolated using suitable techniques such as chromatography and/or extraction techniques; and (5) the molecule(s) from the radioactive fractions obtained in step 4 are characterized using suitable analysis techniques such as chromatography and/or mass spectrometry.