The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2009

Filed:

Jan. 14, 2005
Applicants:

Joseph F. Bringley, Rochester, NY (US);

Tiecheng A. Qiao, Webster, NY (US);

John W. Harder, Rochester, NY (US);

Andrew Wunder, Lyons, NY (US);

James M. Hewitt, Fairport, NY (US);

Inventors:

Joseph F. Bringley, Rochester, NY (US);

Tiecheng A. Qiao, Webster, NY (US);

John W. Harder, Rochester, NY (US);

Andrew Wunder, Lyons, NY (US);

James M. Hewitt, Fairport, NY (US);

Assignee:

Carestream Health, Inc., Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); B01J 13/00 (2006.01); C09D 11/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a composition comprising a colloid which is stable under physiological pH and ionic strength, said colloid comprising particles having a silica core and a shell: a) wherein said shell comprises a cross-linked poly(ethylene)imine polymer having amine functionalities; b) wherein the particles have a volume-weighted mean particle size diameter of less than 200 nm, and c) wherein greater than 50% of said polymer in the colloid is bound to the core surfaces, wherein the polymer having amine functionalities has an average molecular weight less than 100,000 g/mol, the composition has a H of between 6 and 8; and d) wherein the colloid contains between 300 and 6000 .μmol amine-monomer/g core particles.


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