The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2009
Filed:
Nov. 14, 2005
Oded Friedman, Yehiel, IL;
Boris Freger, Beer Sheva, IL;
Olga Etlin, Beer Sheva, IL;
Julia Ditkovitch, Beer Sheva, IL;
Edna Danon, Meitar, IL;
Yana Seryi, Beer Sheva, IL;
Guy Davidi, Even Yehuda, IL;
Oded Arad, Rehovot, IL;
Joseph Kaspi, Givatayim, IL;
Oded Friedman, Yehiel, IL;
Boris Freger, Beer Sheva, IL;
Olga Etlin, Beer Sheva, IL;
Julia Ditkovitch, Beer Sheva, IL;
Edna Danon, Meitar, IL;
Yana Seryi, Beer Sheva, IL;
Guy Davidi, Even Yehuda, IL;
Oded Arad, Rehovot, IL;
Joseph Kaspi, Givatayim, IL;
Chemagis Ltd., Bnei Brak, IL;
Abstract
Provided is a method for preparing letrozole, which includes reacting an activated bis-(4-cyanophenyl)-methane with a triazole to produce letrozole, and, optionally, purifying the letrozole. Also provided are highly pure letrozole, and a method of purifying letrozole, which method includes precipitating letrozole, e.g., by selective precipitation from a reaction mixture and/or by subjecting the letrozole to one or more crystallizations.