The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2009

Filed:

Jun. 10, 2004
Applicants:

Shinji Nara, Sunto-gun, JP;

Hiroshi Nakagawa, Sunto-gun, JP;

Yutaka Kanda, Tokyo, JP;

Takayuki Nakashima, Sunto-gun, JP;

Shiro Soga, Rockville, MD (US);

Jiro Kajita, Sunto-gun, JP;

Jun-ichi Saito, Sunto-gun, JP;

Yukimasa Shiotsu, Sunto-gun, JP;

Shiro Akinaga, Sunto-gun, JP;

Inventors:

Shinji Nara, Sunto-gun, JP;

Hiroshi Nakagawa, Sunto-gun, JP;

Yutaka Kanda, Tokyo, JP;

Takayuki Nakashima, Sunto-gun, JP;

Shiro Soga, Rockville, MD (US);

Jiro Kajita, Sunto-gun, JP;

Jun-ichi Saito, Sunto-gun, JP;

Yukimasa Shiotsu, Sunto-gun, JP;

Shiro Akinaga, Sunto-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/22 (2006.01); C07C 49/303 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; Rrepresents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONRRor the like; Rrepresents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; Rand R, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and Rand R, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.


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