The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2009
Filed:
Mar. 16, 2005
Charles A. Hales, Lincoln, MA (US);
Hari G. Garg, Belmont, MA (US);
Lunyin Yu, Allston, MA (US);
Robert J Linhardt, Albany, NY (US);
Charles A. Hales, Lincoln, MA (US);
Hari G. Garg, Belmont, MA (US);
Lunyin Yu, Allston, MA (US);
Robert J Linhardt, Albany, NY (US);
The General Hospital Corporation, Boston, MA (US);
The University of Iowa Research Foundation, Iowa City, IA (US);
Abstract
This invention provides a method for inhibiting or preventing the abnormal growth of cells, including transformed cells, by administering an effective amount of O-acylated heparin derivative. Abnormal growth of cells refers to cell growth independent of normal regulatory mechanism (e.g. loss of contact inhibition). This includes the abnormal growth of: (1) tumor cells (tumors); (2) benign and malignant cells of other proliferative disease in which aberrant cellular proliferation occurs; (3) aberrant smooth muscle cell proliferation, such as might occur following treatment for coronary atherosclerosis such as angioplasty or the insertion of a stent into an occluded vessel.