The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2009
Filed:
Oct. 20, 2003
Applicants:
Joseph Loscalzo, Dover, MA (US);
Joseph A. Vita, Hingham, MA (US);
Michael D. Loberg, Boston, MA (US);
Manuel Worcel, Boston, MA (US);
Inventors:
Joseph Loscalzo, Dover, MA (US);
Joseph A. Vita, Hingham, MA (US);
Michael D. Loberg, Boston, MA (US);
Manuel Worcel, Boston, MA (US);
Assignee:
NitroMed, Inc., Lexington, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/52 (2006.01); B82B 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a composition comprising an antioxidant, and at least one of isosorbide dinitrate and isosorbide mononitrate in therapeutically effective dosage of each of the aforementioned compounds to treat cardiovascular diseases caused by nitric oxide (NO) insufficiency. The antioxidant is a hydralazine compound.