The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2009

Filed:

Jul. 08, 2005
Applicants:

Sandro Belvedere, Verona, IT;

Joey Lee Methot, Westwood, MA (US);

Thomas A. Miller, Brookline, MA (US);

David J. Witter, Norfolk, MA (US);

Jiaming Yan, New York, NY (US);

Inventors:

Sandro Belvedere, Verona, IT;

Joey Lee Methot, Westwood, MA (US);

Thomas A. Miller, Brookline, MA (US);

David J. Witter, Norfolk, MA (US);

Jiaming Yan, New York, NY (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 259/04 (2006.01); A61K 31/19 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to hydroxamic acid derivatives having a sulfonamide linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.


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