The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2009
Filed:
Sep. 30, 2003
Syunsuke Ohhashi, Kanagawa, JP;
Kazuhiro Kubo, Kanagawa, JP;
Chika Itoh, Kanagawa, JP;
Tohru Yasukohchi, Kanagawa, JP;
Hiroshi Kikuchi, Tokyo, JP;
Norio Suzuki, Chiba, JP;
Miho Kurosawa, Shizuoka, JP;
Hitoshi Yamauchi, Tokyo, JP;
Syunsuke Ohhashi, Kanagawa, JP;
Kazuhiro Kubo, Kanagawa, JP;
Chika Itoh, Kanagawa, JP;
Tohru Yasukohchi, Kanagawa, JP;
Hiroshi Kikuchi, Tokyo, JP;
Norio Suzuki, Chiba, JP;
Miho Kurosawa, Shizuoka, JP;
Hitoshi Yamauchi, Tokyo, JP;
NOF Corporation, Tokyo, JP;
Daiichi Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A phospholipid derivative, utilizable for modification of liposomes and the like, which is a copolymer containing, as essential component units, a component unit A represented by the formula (1), a component unit B represented by the formula (2A) and/or the formula (2B), and a component unit C represented by the formula (3) [Rand Rrepresent hydrogen atom or methyl group, provided that Rand Rdo not simultaneously represent methyl group; Rrepresents a divalent hydrocarbon group having 1 to 3 carbon atoms; AO represents an oxyalkylene group having 2 to 4 carbon atoms; m represents an average molar number of the added oxyalkylene groups and is a number in the range represented as 4≦m≦100; Rrepresents hydrogen atom, a hydrocarbon group or acyl group having 1 to 20 carbon atoms; RCO and RCO represent an acyl group having 8 to 24 carbon atoms; Rrepresents a divalent hydrocarbon group having 2 to 4 carbon atoms; and X and Y represent hydrogen atom, an alkali metal atom, ammonium or an organic ammonium] wherein a molar ratio of the component unit A relative to a total of the component unit B and the component unit C is from 7/3 to 3/7, and the component unit C is contained at a ratio of from 1 to 4 moles per 1 mole of the copolymer.