The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2009
Filed:
Dec. 05, 2001
Takayuki Namiki, Yokohama, JP;
Kenichi Kishii, Yokohama, JP;
Masaki Mitani, Yokohama, JP;
Masashi Tamai, Yokohama, JP;
Naoki Hiyama, Yokohama, JP;
Makoto Kimura, Yokohama, JP;
Satoshi Ichinomiya, Yokohama, JP;
Takayuki Namiki, Yokohama, JP;
Kenichi Kishii, Yokohama, JP;
Masaki Mitani, Yokohama, JP;
Masashi Tamai, Yokohama, JP;
Naoki Hiyama, Yokohama, JP;
Makoto Kimura, Yokohama, JP;
Satoshi Ichinomiya, Yokohama, JP;
Pola Chemical Industries, Inc., Shizuoka-shi, JP;
Abstract
Biphenyl derivatives represented by the following formula (1): wherein Rrepresents a Calkyl group, Rrepresents a substituted or unsubstituted aromatic hydrocarbon, or cycloalkyl group, Rrepresents a tetrazolyl group, —NHCOCF, —NHSOCFor —SONHCONHRin which Rrepresents a substituted or unsubstituted aromatic hydrocarbon group, and Z represents a single bond, a Calkylene group or —SONH—, and salts thereof; and ACAT inhibitors and medicines containing them as active ingredients. The compounds according to the present invention possess excellent ACAT inhibitory activities, and are useful as preventives and/or therapeutics for diseases cased by the enhancement of ACAT activity, for example, hypercholesterolemia, atherosclerosis and the like.