The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2009

Filed:

Feb. 27, 2004
Applicants:

Osamu Irie, Tsukuba, JP;

Genji Iwasaki, Tsukuba, JP;

Keiichi Masuya, Tsukuba, JP;

Takahiro Miyake, Tsukuba, JP;

Naoki Teno, Ushiku, JP;

Inventors:

Osamu Irie, Tsukuba, JP;

Genji Iwasaki, Tsukuba, JP;

Keiichi Masuya, Tsukuba, JP;

Takahiro Miyake, Tsukuba, JP;

Naoki Teno, Ushiku, JP;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds of formula (I) or a pharmaceutically acceptable salt or ester thereof formula (I) wherein the symbols have the meaning as defined in the description. Said compounds are inhibitors of cathepsin K and/or cathepsin S and are useful for the treatment of diseases and medical conditions in which cathepsin K and/or cathepsin S is implicated, e.g. various disorders including neuropathic pain, inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis, multiple sclerosis and tumors.


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