The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2009

Filed:

Feb. 25, 2005
Applicants:

Tomohiro Matsushima, Tsukuba, JP;

Keiko Takahashi, Tsukuba, JP;

Setsuo Funasaka, Tsukuba, JP;

Hiroshi Obaishi, Tsukuba, JP;

Inventors:

Tomohiro Matsushima, Tsukuba, JP;

Keiko Takahashi, Tsukuba, JP;

Setsuo Funasaka, Tsukuba, JP;

Hiroshi Obaishi, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/75 (2006.01); C07D 239/48 (2006.01); C07D 239/47 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [Rrepresents Calkyl or the like; Rand Rrepresent hydrogen; R, R, R, and Rmay be the same or different and each represents hydrogen, halogen, Calkyl or the like; Rrepresents hydrogen or the like; Rrepresents Calkyl or the like; Vrepresents oxygen or the like; Vrepresents oxygen or sulfur; W represents —NH— or the like; X represents —CH═, nitrogen or the like; and Y represents oxygen or the like.]


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