The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2009

Filed:

Mar. 18, 2005
Applicants:

Anthony Atala, Winston Salem, NC (US);

James Yoo, Winston Salem, NC (US);

Grace Lim, Winston-Salem, NC (US);

Richard Czerw, Clemmons, NC (US);

Shay Soker, Greensboro, NC (US);

Joel Stitzel, Winston-Salem, NC (US);

Inventors:

Anthony Atala, Winston Salem, NC (US);

James Yoo, Winston Salem, NC (US);

Grace Lim, Winston-Salem, NC (US);

Richard Czerw, Clemmons, NC (US);

Shay Soker, Greensboro, NC (US);

Joel Stitzel, Winston-Salem, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/70 (2006.01); A61K 33/00 (2006.01); A61K 33/36 (2006.01); A61K 33/32 (2006.01); A61K 33/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed to methods and compositions for preparing matrices for controlled delivery of at least one therapeutic or biological agent to a target site in a subject. This is accomplished using nanoparticles coupled to the therapeutic or biological agent that are incorporated within the matrix or reacted on the surface of the matrix.


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