The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7528133 B1

PDF
Full Text
Expired
Date of Patent:
May. 05, 2009

Filed:

Oct. 29, 1999
Applicants:

John A. Copland, Iii, Houston, TX (US);

Kirk L. Ives, Dickinson, TX (US);

Melvyn Soloff, Galveston, TX (US);

Inventors:

John A. Copland, III, Houston, TX (US);

Kirk L. Ives, Dickinson, TX (US);

Melvyn Soloff, Galveston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/50 (2006.01); A61K 31/501 (2006.01); A61K 31/47 (2006.01); A61K 31/445 (2006.01); A61K 31/41 (2006.01); C07D 239/42 (2006.01); A01N 43/76 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods of preventing or reducing oxytocin-mediated action by using a thiazolidinedione, such as troglitazone, or thiazolidinedione-like compounds. These methods describe the employment of these compounds alone or in combination with at least one other agent, such as a tocolytic agent. This offers a novel therapeutic regimen for the treatment of oxytocin-mediated actions, for example induction of uterine contractions, prostaglandin release, and milk letdown. Accordingly, conditions such as preterm labor and labor prior to Caesarian delivery can be treated by these methods.


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