The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2009
Filed:
Mar. 22, 2005
Julie A. Fruetel, Livermore, CA (US);
Gregory J. Fiechtner, Bethesda, MD (US);
Dahv A. V. Kliner, San Ramon, CA (US);
Andrew Mcilroy, Livermore, CA (US);
Julie A. Fruetel, Livermore, CA (US);
Gregory J. Fiechtner, Bethesda, MD (US);
Dahv A. V. Kliner, San Ramon, CA (US);
Andrew McIlroy, Livermore, CA (US);
Sandia Corporation, Livermore, CA (US);
Abstract
The present embodiment describes a miniature, microfluidic, absorption-based sensor to detect proteins at sensitivities comparable to LIF but without the need for tagging. This instrument utilizes fiber-based evanescent-field cavity-ringdown spectroscopy, in combination with faceted prism microchannels. The combination of these techniques will increase the effective absorption path length by a factor of 10to 10(to ˜1-), thereby providing unprecedented sensitivity using direct absorption. The coupling of high-sensitivity absorption with high-performance microfluidic separation will enable real-time sensing of biological agents in aqueous samples (including aerosol collector fluids) and will provide a general method with spectral fingerprint capability for detecting specific bio-agents.