The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2009
Filed:
Nov. 16, 2006
Bellur S. Prabhakar, Oak Brook, IL (US);
Mark J. Holterman, River Forest, IL (US);
Chenthamarakshan Vasu, Chicago, IL (US);
Matthew N. Meriggioli, Clarendon Hills, IL (US);
Bellur S. Prabhakar, Oak Brook, IL (US);
Mark J. Holterman, River Forest, IL (US);
Chenthamarakshan Vasu, Chicago, IL (US);
Matthew N. Meriggioli, Clarendon Hills, IL (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Abstract
GM-CSF administered before immunization exerted a sustained suppressive effect against the induction of myasthenia gravis (MG). This suppression was associated with lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion in the population of FoxP3+ regulatory T cells. Manipulating DCs to expand regulatory T cells is useful for the control of autoimmune diseases such as myasthenia gravis MG.