The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Jul. 23, 2003
Kenichi Koyakumaru, Bizen, JP;
Yoshimi Fukunaga, Chiyoda-ku, JP;
Youichi Satake, Kurashiki, JP;
Kuraray Co., Ltd., Kurashiki-shi, JP;
Eisai R & D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a method of industrially and advantageously producing a 5-(2'-pyridyl)-2-pyridone derivative. The present invention relates to a production method of a 5-(2′-pyridyl)-2-pyridone derivative represented by the formula (VI), which includes reacting a pyridine derivative of the formula (I) with a brominating agent to give a 5-bromopyridine derivative of the formula (II), reacting the obtained 5-bromopyridine derivative with a metallizing agent to give an organometallic compound of the formula (III), reacting the obtained organometallic compound with a 2-sulfonylpyridine derivative of the formula (IV) to give a 6-alkoxy-3,2′-bipyridine derivative of the formula (V) and hydrolyzing the obtained 6-alkoxy-3,2′-bipyridine derivative: wherein each symbol is as defined in the Description.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile