The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Nov. 13, 2003
Keita Nishino, Hyogo, JP;
Teruyoshi Koga, Hyogo, JP;
Keita Nishino, Hyogo, JP;
Teruyoshi Koga, Hyogo, JP;
Kaneka Corporation, Osaka, JP;
Abstract
The present invention provides a process for efficiently producing a 1β-methylcarbapenem compound for oral administration. The process, which is for producing a 1β-methylcarbapenem compound represented by general formula (2), is characterized by reacting a β-lactam compound represented by general formula (1) as a starting material with a thiol compound (R—SH) in the presence of a base and optionally eliminating the protective group R. In the formulae (1) and (2), Rdenotes a hydrogen atom, a trimethylsilyl group or a triethylsilyl group; Rdenotes an alkyl group having 1 to 10 carbon atoms or a cycloalkyl group having 3 to 10 carbon atoms; Rdenotes an organic group; and Rdenotes hydrogen, a trimethylsilyl group or a triethylsilyl group.