The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Aug. 05, 2002
Mary Ann Pelleymounter, Thousand Oaks, CA (US);
Randy Ira Hecht, Thousand Oaks, CA (US);
Michael Benjamin Mann, Thousand Oaks, CA (US);
Mary Ann Pelleymounter, Thousand Oaks, CA (US);
Randy Ira Hecht, Thousand Oaks, CA (US);
Michael Benjamin Mann, Thousand Oaks, CA (US);
Amgen, Inc., Thousand Oaks, CA (US);
Abstract
The present invention provides methods and compositions for treating excess weight by administering OB protein in a form for constant supply, at a dosage of less than or equal to about 1 mg protein/kg body weight/day. Compositions and methods used for production of recombinant murine and human OB protein are also provided. Compositions and methods for preparing recombinant murine methionyl OB protein and recombinant human methionyl OB protein, including DNA sequences, vectors, host cells, methods of fermentation, and methods of purification are provided herein.