The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2009

Filed:

May. 25, 2006
Applicants:

Paz Einat, Nes Ziona, IL;

Rami Skaliter, Nes Ziona, IL;

Elena Feinstein, Rehovot, IL;

Aviv Regev, Cambridge, MA (US);

Hagar Kalinski, Rishon-le-Zion, IL;

Inventors:

Paz Einat, Nes Ziona, IL;

Rami Skaliter, Nes Ziona, IL;

Elena Feinstein, Rehovot, IL;

Aviv Regev, Cambridge, MA (US);

Hagar Kalinski, Rishon-le-Zion, IL;

Assignee:

Quark Pharmaceuticals, Inc., Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided polynucleotides that are modulated by hypoxic conditions. The disclosure includes such genes and proteins as well as analogs, salts and functional derivatives of such proteins, and DNA encoding such analogs, and methods of use. Methods for treating the effects of stroke, hypoxia and/or ischemia by regulating such genes or proteins are also disclosed. The presence of hypoxia or a hypoxia-associated pathology may be diagnosed by screening for the presence of at least one polynucleotide having the nucleic acid sequence according to the present invention. Methods of regulating hypoxia associated pathologies are also provided.


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