The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Apr. 30, 2004
Darren Whitehouse, Westbrook, CT (US);
Shaojing HU, Hamden, CT (US);
Haiquan Fang, Madison, CT (US);
Michael C. Van Zandt, Guilford, CT (US);
Darren Whitehouse, Westbrook, CT (US);
Shaojing Hu, Hamden, CT (US);
Haiquan Fang, Madison, CT (US);
Michael C. Van Zandt, Guilford, CT (US);
The Institute for Pharmaceuticals Discovery LLC, Branford, CT (US);
Abstract
Disclosed are compounds and pharmaceutically acceptable salts of formula (A): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of the invention include inhibitors of Protein tyrosine phosphatases, in particular Protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.