The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2009

Filed:

May. 27, 2005
Applicants:

Josephus H. M Lange, Weesp, NL;

Henderik C. Wals, Weesp, NL;

Cornelis G. Kruse, Weesp, NL;

Inventors:

Josephus H. M Lange, Weesp, NL;

Henderik C. Wals, Weesp, NL;

Cornelis G. Kruse, Weesp, NL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 31/4164 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to 1,2,4,5-tetrasubstituted imidazole derivatives as selective cannabinoid CBreceptor modulators, in particular CBreceptor antagonists or inverse agonists having a high CB/CBreceptor subtype selectivity, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said imidazole derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. A beneficial effect is disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. The invention also relates to the use of a compound of the invention for the manufacture of a medicament for treating or preventing a disease or condition. More particularly, the invention relates to a new use for the treatment of a disease or condition disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. In embodiments of the invention specific compounds disclosed herein are used for the manufacture of a medicament useful in the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.


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